[Rotational atherectomy in the drug-eluting stent era: the revival of a forgotten technique?].

نویسنده

  • Jose Baptista
چکیده

Although rotational atherectomy (RA) was first introduced in 1986 as a technique for mechanical thrombectomy,1 it was its potential to reduce barotrauma and hence restenosis that sparked the interest of researchers.2--6 Unlike balloon angioplasty, in which acute luminal gain is obtained through stretching of the arterial wall,7--9 RA works by abrading and thereby debulking atherosclerotic plaques.10 The hope was that RA would reduce restenosis by decreasing the quantity of residual plaque after angioplasty, which several intravascular ultrasound studies have shown is one of the most important predictors of restenosis.11 However, it was found that the loss index, a measure of late luminal loss and thus of the efficacy of the technique in terms of restenosis, was no better than with balloon angioplasty.3 In some series in the pre-stent era, RA was associated with restenosis rates as high as 40%, despite apparently reducing barotrauma and the number of dissections.3 Several studies including DART,3 ERBAC,4 STRATAS5 and CARAT,6 as well as meta-analyses,12 did not support the use of RA as a means of reducing restenosis. As a result the technique fell out of favor and is currently employed in less than 5% of procedures in Europe. The widespread use of bare-metal stents, particularly after 1995, led to a new phenomenon, in-stent restenosis. RA was the obvious technique to treat this since it enabled

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Application of rotational atherectomy in the drug-eluting stent era

Rotational atherectomy (RA) was introduced in the interventional arena in 1988 as a dedicated device for calcified lesions. Due to the complexity of the technique, the development of alternative methods such as the cutting balloon procedure, and the high restenosis rate of subsequent bare metal stenting in long lesions, its use had later declined. However, with the increasing use of drug-elutin...

متن کامل

[Drug-eluting stents and other anti-restenosis devices].

Restenosis remains as the main limitation of percutaneous coronary intervention, even in the era of coronary stents. Recently, drug-eluting stents have been shown to reduce significantly both the rate of in-stent restenosis and the need for subsequent revascularization procedures compared with bare-metal stents. At present, these beneficial effects have been demonstrated mainly with Cypher (Cor...

متن کامل

Two-Year Clinical Outcomes of Newer-Generation Drug-Eluting Stent Implantation Following Rotational Atherectomy for Heavily Calcified Lesions.

BACKGROUND Clinical outcomes of implantation of the newer-generation drug-eluting stent (DES) following rotational atherectomy for heavily calcified lesions remain unclear in the real-world setting. METHODSANDRESULTS We enrolled 252 consecutive patients (273 lesions) treated with newer-generation DES following rotational atherectomy. The primary endpoint was the cumulative 2-year incidence of...

متن کامل

Rotational atherectomy in the drug-eluting stent era: a single-center experience.

BACKGROUND In heavily calcified lesions, rotational atherectomy (RA) improves procedural success and facilitates stent deployment. Reports on RA in the drug-eluting stent (DES) era are limited. The objective of this study was to determine the presenting characteristics, procedural and in-hospital clinical outcomes of patients who underwent RA at our institution in the DES era. METHODS Consecu...

متن کامل

The use of rotational atherectomy and drug-eluting stents in the treatment of heavily calcified coronary lesions.

INTRODUCTION The treatment of calcified coronary artery lesions is a challenge for percutaneous angioplasty. Rotational atherectomy is an established technique for the effective modification of these lesions prior to conventional angioplasty and stent implantation. Drug-eluting stents (DES) have shown encouraging results in complex lesions and high-risk patients. METHODS This retrospective st...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology

دوره 31 1  شماره 

صفحات  -

تاریخ انتشار 2012